One of the most clinically successful heparin technologies has been the Carmeda ® BioActive Surface (CBAS).12, 13 This heparin binding technology is based upon covalent end-point attachment of heparin to a biomaterial surface, enabling maintenance of functional heparin bioactivity.

The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water and air supplies. This enables coating

CARMEDA ® BioActive Surface (also known as CBAS ® Heparin Surface) is the clinically most proven heparin coating technology commercially available. This technology provides a lasting thromboresistance that actively prevents platelet adhesion and thrombus formation on medical device surfaces. End-point attached (EPA) heparin, using the proprietary Carmeda Bioactive Surface (CBAS Surface), was compared with other methods of covalent heparin bonding that typically yield multiple covalent linkages (using reductive amination of periodate oxidized native heparin or EDC coupling of native heparin). 2014-10-31 · Medtronic initiated an Urgent Medical Device Recall for 66 distributed Affinity FusionTM Oxygenation Systems with Carmeda Bioactive Surface due to damaged heat exchangers. Product affected by this issue is limited to model CB841 sold stand alone or incorporated in Total Systems TS1614R1 and TS1595R7.

Euro- pean Journal of Vascular and Endovascular Surgery 2003;25(5):432-437. Consult Medtronic's entire Affinity CP Centrifugal Blood Pump with Carmeda® Bioactive Surface or Balance® Biosurface catalogue on MedicalExpo. Page: 1/4. The effects of Carmeda Bioactive Surface on human blood components during simulated extracorporeal circulation. · Author information · Abstract · Full text links The attempt to coat the artificial surfaces with heparin, an anticoagulant that imitates the 5.1.1 Medtronic Inc. (Carmeda Bioactive Surface®=CBAS).

The left atrium was cannulated using a Carmeda bioactive surface cannula.

The device incorporates Carmeda BioActive Surface (CBAS) technology to bond heparin.15–18 The technology is based on the covalent end-point attachment

In the following experiments, we evaluated the heparin-bonded Carmeda Bioactive Surface (Medtronics Cardiopulmonary, Anaheim, Calif.) in an in vitro model of extracorporeal circulation at standard-dose heparin (5 U/ml), to examine the effects of the surface treatment on activation of blood elements, and at reduced-dose heparin (1 U/ml), to 16. Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX vascular graft performance by Carmeda BioActive surface heparin immobilization. Eur J Vasc Endovasc Surg. 2003;25:432–437 The luminal surface of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive is modified with a covalently bound, bioactive heparin technology referred to as the Carmeda BioActive Surface (CBAS®).

The selection ranges from bioinert or biopassive modification strategies -also in combination with adjusted microstructure and topography, via bioactive and biomimetic modification techniques to endothelial cells (ECs) as biological surface coatings and gene therapeutic approaches.

The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water and air supplies. This enables coating of Class III products according to both European and US requirements. The CBAS Heparin Surface stays on the surface and remains bioactive on the EXCOR pump at least up until 1 year.

J Thorac Cardiovasc Surg . (1996) 111:1073–84.
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The publications within the reference list are divided into the categories of basic 2018-01-01 The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water … The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment.

The luminal surface of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive is modified with a covalently bound, bioactive heparin technology referred to as the Carmeda BioActive Surface (CBAS®). Figure 1: The GORE® VIABAHN® Endoprosthesis . External Nitinol Stent ePTFE Lining One of the most clinically successful heparin technologies has been the Carmeda® BioActive Surface (CBAS). 12, 13 This heparin binding technology is based upon covalent end-point attachment of heparin to a biomaterial surface, enabling maintenance of functional heparin bioactivity.
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Affinity CP Centrifugal Blood Pump with Carmeda® Bioactive Surface or Balance® Biosurface. 4 Pages. Affinity CP Centrifugal Blood Pump Brochure. 4 Pages.

Carmeda AB har 40 anställda och gjorde ett resultat på 127 125 KSEK med omsättning 215 982 KSEK under 2001 jämförde de kliniska resultaten från 1336 patienter med Carmeda Bioactive Surface och Duraflo II-beläggningarna. Forskarna drog The CARMEDA ® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices. It is the most clinically proven thromboresistant surface coating available on the market. The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces. The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies and scientific papers: The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces.